Bph and sperm damage

Benign prostatic hyperplasia BPH is one of the most common reproductive disorders in both male dogs and men. Although sperm can be affected by both BPH and finasteride treatment, the direct influence on DNA integrity remains unclear. Sperm DNA integrity was not affected by finasteride treatment. In conclusion, benign prostatic hyperplasia causes post-testicular sperm DNA damage, albeit finasteride treatment itself does not directly influence sperm DNA integrity.
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25.01.2021
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Benign Prostatic Hyperplasia (BPH): Symptoms, Diagnosis & Treatment - Urology Care Foundation

BPH is an enlarged prostate. The first occurs early in puberty, when the prostate doubles in size. The second phase of growth starts around age 25 and goes on for most of the rest of a man's life. BPH most often occurs during this second growth phase. As the prostate enlarges, it presses against the urethra.
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The role of the prostate in male fertility, health and disease

Benign prostatic hyperplasia BPH has a high incidence in older intact dogs. Due to the increased prostatic oxidative stress and hormonal imbalance of BPH, sperm damage can arise, such as sperm morphological alterations and DNA fragmentation. This study aimed to compare the reproductive potential of healthy dogs and those affected by benign prostatic hyperplasia. Three semen collections were performed from each dog within one month and analysed using computer-assisted sperm analysis CASA and functional tests. On the other hand, the percentage of minor sperm defects, amplitude of lateral sperm head displacement of the spermatozoa and medium sperm mitochondrial activity were higher in the BPH group.
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One in five men will experience a problem with their prostate at some point in their lives. A small gland situated below the bladder, a troublesome prostate can cause sexual problems and make it difficult to urinate. This article will outline the three most common problems associated with the prostate, an enlarged prostate Benign Prostatic Hyperplasia BPH , prostatitis and prostate cancer.
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